Dr. Cletus Ukwubile | Nanomedicine | Research Excellence Award
University of Maiduguri | Nigeria
Dr. Cletus Ukwubile is a pharmacognosy researcher whose work integrates natural product chemistry, analytical instrumentation, and biomedical investigation. His expertise spans advanced chromatographic and spectroscopic techniques, including GC-MS, HPLC, TLC, PTLC, and VLC, which he applies to the characterization of bioactive compounds from medicinal plants. He has extensive experience in statistical and data-driven research using SPSS, GraphPad, R, SQL, and Tableau to support evidence-based scientific inquiry. His research contributions include leadership in university-level pharmacognostic studies and cancer-related investigations, particularly through funded projects such as the TETFund Nigeria Institutional Based Research Grant for brain tumour research. He has also benefited from international training, including a Royal Society of Chemistry fellowship in GC-MS analytics. With additional involvement in scientific societies and editorial bodies, he contributes to advancing natural product research, pharmacological discovery, and translational applications in biomedical science.
Featured Publications:
Ukwubile, C. A., Robert, A. E., Nuhu, A., Ahuchaogu, A. A., Ikpefan, E. O., & others. (2026). Nano-enhanced phytotherapy of prostate cancer: Evaluating the combined efficacy of Telfairia occidentalis seed and Annona muricata leaf extracts. Fitoterapia, 188, 106998.
Ukwubile, C. A., Robert, A. E., Ezema, B. O., Yesufu, H. B., Famurewa, A. C., Ikpefan, E. O., & others. (2025). Methanol extract of young Lantana camara leaves exhibits anti-ovarian cancer and anti-inflammatory effects via inhibition of PI3K/AKT/mTOR and MAPK pathways. Chemistry & Biodiversity, e01758.
Ukwubile, C. A., Clement, C. K., Ijoh, B. B., & others. (2025). Evaluation of anticancer and anti-inflammatory properties of Crescentia cujete and Citrullus vulgaris methanol seed extracts against MCF-7 breast cancer cells and molecular docking. Dutse Journal of Pure and Applied Sciences, 11(3e), 260–273.
Ukwubile, C. A., & Malgwi, T. S. (2025). Lantana camara leaf extract-loaded chitosan nanoparticles induce apoptosis and suppress PI3K/AKT and NF-κB signalling in triple-negative breast and colorectal cancer cells. Journal of Pharmacy & Bioresources, 22(3), 185–194.
Ukwubile, C. A., Lawan, M. Z., Malgwi, T. S., Yesufu, H. B., & others. (2025). Evaluation of anti-inflammatory and anticancer activities of Maerua angolensis leaf extract-loaded chitosan nanoparticles. Biomaterials Connect, 2, Article 0018.
Ukwubile, C. A., Yesufu, B. H., Okoro, N. R., & others. (2025). Chitosan-encapsulated linoleic acid from Leucaena leucocephala inhibits FOXL2 mutation in MNU-induced ovarian granulosa cell tumors in Wistar rats. Next Nanotechnology, 8, 100191.
Ukwubile, C. A., Nuhu, A., Famurewa, A. C., Nettey, H., Odugu, J. A., & others. (2025). Chitosan nanoparticles encapsulating Ipomoea digitata tuber and Jatropha gossypiifolia leaf extracts suppress NF-κB, Wnt/β-catenin, and MAPK signalling pathways in colorectal cancer cells. International Journal of Advanced Multidisciplinary Research and Studies, 5(5), 45–58.
Dibal, M. Y., Ukwubile, C. A., Ibrahim, H., Malgwi, T. S., Mohammed, Z., & others. (2025). Pharmacognostic and phytochemical studies of the leaves and stembark of Anogeissus leiocarpus. Journal of Medical Research and Reviews, 4(3), 89–105.
Ikpefan, E. O., & Ukwubile, C. A. (2025). GC-MS analysis and evaluation of analgesic and anticancer activities of Cadaba farinosa methanol leaf extract. Academic Journal of Pharmacy & Biomedical Sciences, 2(1), 10–18.