Ranran Li | Signal Transduction Mechanisms | Best Researcher Award

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Dr. Ranran Li | Signal Transduction Mechanisms | Best Researcher Award

Ranran Li , Ruijin Hospital, Shanghai Jiao Tong University School of Medicine , China

Dr. Ranran Li is an associate researcher at Ruijin Hospital, Shanghai Jiao Tong University School of Medicine in Shanghai, China. She earned her Ph.D. from the University Medical Center of Groningen, Netherlands, in 2015, before returning to Shanghai to focus on critical care medicine. Her research centers on sepsis-associated endothelial dysfunction and its underlying molecular mechanisms. Over the years, Dr. Li’s work has provided valuable insights into the role of metabolic disorders and post-translational modifications in regulating endothelial inflammation and coagulation during sepsis. She has published extensively in reputable journals and holds several patents. Her recent findings suggest potential therapeutic targets for the treatment of sepsis and related complications, including endothelial dysfunction and organ injury.

Publication Profile:

Scopus

Strengths for the Award:

Dr. Ranran Li is a distinguished researcher with notable expertise in the mechanisms of sepsis-associated endothelial dysfunction. Her work in identifying the role of metabolic disorders and post-translational modifications in sepsis has been pivotal in advancing the understanding of vascular inflammation and coagulation during critical illness. Her research has led to several high-impact publications and patents, showcasing her contributions to the field. Furthermore, Dr. Li’s interdisciplinary approach, combining metabolic biology, cell signaling, and translational medicine, has provided valuable therapeutic targets for the treatment of sepsis and endothelial dysfunction. Her collaborations with international experts enhance her work’s impact and broaden the scope of her research.

Areas for Improvements:

While Dr. Li’s research has been extensive and groundbreaking, future improvements could include increased collaborations with industry partners to accelerate the translation of her findings into clinical therapies. Expanding her professional network through international collaborations in other areas of critical care medicine could also provide new perspectives and avenues for innovation. Additionally, engaging in larger-scale clinical studies might help further validate her findings in human models.

Education

Dr. Ranran Li obtained her Ph.D. in Medical Sciences from the University Medical Center of Groningen, Netherlands, from 2011 to 2015. During her doctoral studies, she focused on the molecular mechanisms of sepsis and its impact on vascular endothelial dysfunction. Her Ph.D. research laid the foundation for her ongoing investigations into the pathophysiology of sepsis and endothelial injury. Following her Ph.D., she joined Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, in 2016 as an associate researcher in the Department of Critical Care Medicine. Here, Dr. Li furthered her research into sepsis, vascular inflammation, and metabolic disorders. She has developed an expertise in endothelial dysfunction and coagulation, specifically in the context of sepsis-induced organ injuries. Dr. Li’s comprehensive academic training, both in Europe and China, has significantly contributed to her innovative research work and international collaborations.

Experience:

Dr. Ranran Li has been serving as an associate researcher at Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, since 2016. Prior to this, she earned her Ph.D. from the University Medical Center of Groningen in the Netherlands, where she focused on sepsis and endothelial dysfunction. In her current position, Dr. Li has worked extensively on understanding the mechanisms underlying sepsis-associated endothelial dysfunction, with a particular focus on metabolic disorders and post-translational modifications. Her work has provided critical insights into the role of fatty acid metabolism, insulin resistance, and histone modifications in regulating endothelial inflammation and coagulation activation in sepsis. Dr. Li’s research has led to multiple publications in high-impact journals and the filing of patents for innovative therapeutic approaches. She collaborates with leading researchers in the Netherlands and has contributed significantly to the understanding of vascular injury and its therapeutic targets in sepsis.

Research Focus:

Dr. Ranran Li’s research focuses on the molecular mechanisms of sepsis-associated endothelial dysfunction, with a particular emphasis on metabolic disorders and post-translational modifications. She has been exploring how fatty acid metabolism, glucose-lipid metabolism, and protein acetylation influence endothelial cells during sepsis, leading to organ injury. Her research has highlighted the role of metabolic shifts, including the activation of pathways like AMPK/PKA, in endothelial inflammation and coagulation activation. Dr. Li has also studied the role of histone modifications, including lactylation, in promoting endothelial ferroptosis and dysfunction during sepsis-induced lung injury. She has been pioneering the exploration of metabolic signaling pathways and their potential as therapeutic targets for managing sepsis-related endothelial damage. Her work aims to identify novel strategies to prevent or mitigate vascular injury in septic patients. Dr. Li’s findings have led to both patents and high-impact publications in critical care and translational medicine.

Publications Top Notes:

  1. Shiyuan He et al., Fatty acid synthesis promotes mtDNA release via ETS1-mediated oligomerization of VDAC1 facilitating endothelial dysfunction in sepsis-induced lung injury 🧬🫁 Cell Death and Differentiation, 2025
  2. Ranran Li et al., ATP-citrate lyase controls endothelial gluco-lipogenic metabolism and vascular inflammation in sepsis-associated organ injury 💉🧪 Cell Death and Disease, 2023
  3. Jie Liu et al., Designed microchannel-based lipid nanoparticles encapsulated siRNA targeting gasdermin D for sepsis management via pulmonary delivery 🧬💉 Nano Today, 2025
  4. Fangchen Gong et al., H3K14la drives endothelial dysfunction in sepsis-induced ARDS by promoting SLC40A1/transferrin-mediated ferroptosis 🧬🔥 MedComm, 2025
  5. Jiayin Cui et al., Herbal-based Xuebijing injection ameliorated vascular endothelial dysfunction via inhibiting ACLY/MYB/RIG-I axis in sepsis-associated lung injury 🌱💊 Phytomedicine, 2025
  6. Shasha Lu et al., GDF15 ameliorates sepsis-induced lung injury via AMPK-mediated inhibition of glycolysis in alveolar macrophage 💨🧪 Respiratory Research, 2024
  7. Rui Tian et al., Shenfu injection ameliorates endotoxemia-associated endothelial dysfunction and organ injury via inhibiting PI3K/Akt-mediated glycolysis 💉🫀 Journal of Ethnopharmacology, 2024
  8. Yupeng Zhao et al., H3K18 lactylation-mediated VCAM1 expression promotes gastric cancer progression and metastasis via AKT-mTOR-CXCL1 axis 🎗️🧬 Biochemical Pharmacology, 2024
  9. Rui Tian et al., Metformin ameliorates endotoxemia-induced endothelial pro-inflammatory responses via AMPK-dependent mediation of HDAC5 and KLF2 💊💉 BBA-Molecular basis of disease, 2019
  10. Lei Pei et al., MSCs-derived extracellular vesicles alleviate sepsis-associated liver dysfunction by inhibiting macrophage glycolysis-mediated inflammatory response 🧬🩸 International Immunopharmacology, 2024

Conclusion:

Dr. Ranran Li is highly deserving of the Best Researcher Award due to her outstanding contributions to understanding the molecular mechanisms underlying sepsis-related endothelial dysfunction. Her innovative research has not only provided deep insights into the pathophysiology of sepsis but has also uncovered potential therapeutic targets for treating this devastating condition. Her exceptional track record of high-quality publications, patents, and collaborative research, combined with her dedication to advancing critical care medicine, makes her an excellent candidate for this prestigious award.

SATISH SAW | Cell Death Pathway | Best Researcher Award

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Mr. SATISH SAW | Cell Death Pathway | Best Researcher Award

Mr. SATISH SAW , VINOBA BHAVE UNIVERSITY, HAZARIBAG, JHARKHAND , India

Satish Saw is a Senior Research Fellow in the University Department of Physics at Vinoba Bhave University, Hazaribag, India. He is also a PGT teacher in the Jharkhand Government. His Ph.D. research focuses on “Computational and Experimental studies of Soft- and Hard-Nanomaterials.” With a strong background in Condensed Matter Physics, NanoBio Systems, and Electronics, Satish has demonstrated academic excellence through his education, research, and teaching. He has participated in numerous national and international conferences and workshops. Along with his academic endeavors, Satish has contributed to several publications in reputed journals, enhancing the field of nanomaterials, biodiesel, and environmental sciences. He has received several prestigious awards, including the Gold Medal in M.Sc. and the UGC Junior and Senior Research Fellowships. His dedication to research, along with his teaching responsibilities, highlights his well-rounded commitment to the field of physics.

Publication Profile:

Google Scholar

Strengths for the Award:

  1. Academic Excellence:
    • Gold Medal in M.Sc. and College Topper in B.Sc.: Demonstrates consistent academic achievement.
    • UGC Junior Research Fellowship (2022-2024) and Senior Research Fellowship (2024-Present) show significant recognition of his research capabilities.
    • Completion of Ph.D. with a focus on advanced topics like Condensed Matter Physics and NanoBio Systems.
  2. In-depth Research Contributions:
    • Innovative Research in Nanomaterials: Satish Saw has extensively researched nanomaterials, especially green synthesis of ZnO, Ag-ZnO, and gold nanoparticles. His work in DFT (Density Functional Theory) calculations and experimental techniques has great potential in real-world applications.
    • Cross-disciplinary Collaboration: He has co-authored several papers with diverse researchers, spanning fields like materials science, biotechnology, and environmental science.
    • Multiple research papers under review and accepted, demonstrating high productivity and ongoing contributions to the scientific community.
  3. Research Funding & Recognition:
    • Active participation in high-profile conferences, such as the 66th DAE- Solid state physics symposium, and international events like ASTM-2024 at IIT ISM and Ecotoxicology and Environmental Science Conference at Amity University. These indicate strong networking and engagement with the broader scientific community.
    • His research outputs have already found communication in reputable journals like Physics Letters A and International Journal of Hydrogen Energy, showcasing a broad research impact.
  4. Multidisciplinary Skills:
    • Knowledge of computational methods (Quantum Espresso DFT Software), experimental techniques, and software like Origin Software.
    • Proficiency in multiple areas, including Solid State Physics, Classical Mechanics, Quantum Mechanics, and Mathematical Physics.
  5. Awards & Recognition:
    • Recognition through various fellowships, including UGC JRF & SRF, which are competitive and honor the best researchers.
    • His significant contribution in identifying quasi-specific binding sites of proteins and advancing the understanding of nanomaterial applications makes him stand out.

Areas for Improvement:

  1. Broader Impact and Outreach:
    • While his research is technically impressive, expanding efforts into outreach activities, such as engaging in more public seminars or popular science communication, could further enhance the visibility of his research and its societal impact.
  2. Interdisciplinary Cross-pollination:
    • Although Satish’s research covers a wide range of topics, further interdisciplinary collaborations between bioinformatics and environmental sustainability could push his research into the global forefront, especially concerning sustainable energy solutions or eco-friendly materials.
  3. Publication Diversity:
    • While he has many ongoing or accepted papers, targeting a few high-impact factor journals in his specific fields of interest could elevate the overall reach and recognition of his work.
  4. Experimental Work Expansion:
    • Despite his extensive theoretical knowledge, additional experimental validation, such as large-scale studies or industrial collaborations, could bolster his research’s real-world applicability, especially in nanomaterials for environmental or industrial applications.

Education:

Satish Saw completed his Ph.D. in Condensed Matter Physics and NanoBio Systems at Vinoba Bhave University, Hazaribag. Prior to that, he earned his B.Ed. in Physical Science and M.Sc. in Electronics from the same institution. His undergraduate journey included a B.Sc. in Physics, followed by I.Sc. with a focus on Physics, Chemistry, Mathematics, and Economics. Throughout his academic journey, Satish consistently exhibited strong performance, culminating in his ongoing Ph.D. research in advanced nanomaterials. With a specialization in Solid-State Physics, Quantum Mechanics, and other physics-related disciplines, Satish developed an in-depth understanding of theoretical and experimental physics. His education has paved the way for his diverse academic and professional contributions, including his mastery of software like Quantum Espresso DFT and Origin Software, which aid in his research work. His knowledge base is further supported by his strong foundation in mathematical and classical mechanics.

Experience:

Satish Saw brings a wealth of experience in both academic and research fields. As a Senior Research Fellow at the University Department of Physics, Vinoba Bhave University, Hazaribag, he has conducted extensive research on nanomaterials, both computationally and experimentally. He also serves as a PGT teacher in the Jharkhand Government, where he imparts knowledge in Physics. His professional experience includes attending several prominent national and international conferences, such as the “66th DAE-Solid State Physics Symposium” and the “International Conference on Ecotoxicology and Environmental Science.” Furthermore, he has undergone specialized training in “Research Equipment in Physics & Biotechnology” at CUSB, Gaya. His deep knowledge in Solid-State Physics, Quantum Mechanics, and computational modeling has allowed him to collaborate with professionals worldwide, advancing his field. His expertise is not only theoretical but also hands-on, making him a versatile academician and researcher in modern physics.

Awards & Honors:

Satish Saw has earned numerous awards and honors in recognition of his academic and research excellence. He was awarded the Gold Medal in his Master of Science (M.Sc.) program for academic excellence. Additionally, he was recognized as the College Topper during his Bachelor of Science (B.Sc.) studies. Satish’s dedication to research has earned him the prestigious UGC Junior Research Fellowship (JRF) in January 2022, which he is currently holding. In January 2024, he was promoted to UGC Senior Research Fellowship (SRF), a testament to his continuous contribution to the field. He also qualified for the UGC NET/JRF-2020 and GATE-2020 exams. These accolades reflect his deep commitment to academic growth and research, further positioning him as a leader in his field. Satish’s consistent pursuit of excellence in both academia and research makes him a deserving candidate for various prestigious awards in his field.

Research Focus:

Satish Saw’s primary research focus lies in the computational and experimental study of nanomaterials, particularly in the fields of Condensed Matter Physics and NanoBio Systems. His Ph.D. research is centered on understanding the properties of soft- and hard-nanomaterials through Density Functional Theory (DFT) and other computational techniques, alongside experimental investigations. His work explores the structural, electronic, and optoelectronic properties of nanoparticles, specifically ZnO and Ag-ZnO composites, synthesized using green methods. Additionally, Satish investigates the antibacterial and biocompatibility aspects of these nanoparticles for potential biomedical applications. His research interests extend to the study of biodiesel, specifically its performance and emission characteristics in diesel engines using hydrogen as a secondary fuel. Satish also delves into the synthesis of iodine-doped nanocomposites, focusing on sustainable approaches for material development. His research is pivotal for advancing both materials science and environmental sustainability.

Publications Top Notes:

  1. Morphological, structural, and electronic properties of green synthesized ZnO nanoparticles by experimental and DFT+U method – A review 🌿💎 (Communicated).
  2. Effect on polytropic index, performance, and emission of diesel engine using hydrogen as gaseous fuel with additive di-tert butyl peroxide 🚗⚡ (Communicated).
  3. Identification of quasispecific binding sites of Cro-, λ- and Gal- repressor proteins within Escherichia coli bacterial and Enterobacteria phage λ viral genomes 🧬🔬 (Communicated).
  4. Green synthesis of iodine doped nano-composites using Ocimum basilicum (basil) leaf extract 🌿🔬 (Communicated).
  5. Effect on emissions, combustion, and performance characteristics of Karanja oil biodiesel and Di-tert butyl peroxide assisted using hydrogen as a secondary fuel in a diesel engine 🛢️⚙️ (Communicated).
  6. Experimental and DFT studies of Green Synthesized ZnO nanoparticles for their antibacterial and optoelectronic applications 🦠💡 (Accepted).
  7. Green synthesis of Ag-ZnO Composite nanoparticles using Ocimum basilicum (basil) leaf extract and study their antibacterial effect 🌱💊 (Under Review).
  8. Green synthesis and characterization of gold nanoparticles using leaf extract of Withania somnifera and their in vivo biocompatibility with embryonic zebrafish and antibacterial study 🌟🐟 (Under Review).
  9. Investigation on Pongamia biodiesel with di-tert butyl peroxide on emissions and performance using hydrogen fuel in a diesel engine 🚙🌱 (Under Review).

Conclusion:

Satish Saw stands out as an exemplary researcher due to his academic brilliance, research productivity, and ability to blend theoretical and experimental methodologies in cutting-edge fields like nanomaterials and nanobiotechnology. His consistent achievements, multiple publications in renowned journals, and his engagement with global scientific communities make him a strong candidate for the Best Researcher Award.

 

 

 

Felicia ANTOHE | Molecular Mechanisms Signaling | Molecular Cell Biology Award

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Dr. Felicia ANTOHE | Molecular Mechanisms Signaling | Molecular Cell Biology Award

Dr. Felicia ANTOHE , Inst. Cellular Biology and Pathology NS , Romania

Dr. Felicia Antohe is the Head of the Proteomics Department at the Institute of Cellular Biology and Pathology, Romanian Academy. With a background in cellular biology and biophysics, she has contributed significantly to biomedical research, particularly in vascular endothelium, atherosclerosis, diabetes, and immune disorders. She has received multiple prestigious awards and conducted pioneering research, especially on the transcytosis of macromolecules in endothelial cells. As a PhD advisor, she mentors young researchers, having guided 12 PhD students to date. Dr. Antohe is an internationally recognized expert with extensive experience in immunology, cell biology, and proteomics.

Publication Profile:

Google Scholar

Strengths for the Award:

Dr. Felicia Antohe stands out as an exceptional candidate for the Research for Molecular Cell Biology Award due to her extensive academic and research achievements. As Head of the Proteomics Department at the Institute of Cellular Biology and Pathology, Romanian Academy, her leadership in pioneering research in endothelial cell biology and vascular pathologies has been transformative. Dr. Antohe’s strong academic background, with a Master’s in Biophysics and a PhD in Cellular Biology, complements her robust research portfolio. With over 170 scientific papers, 90 of which are indexed in Web of Science, she is recognized for her contributions to molecular mechanisms in diseases such as atherosclerosis, diabetes, and immune disorders. Furthermore, her work on monoclonal antibodies and proteomics has had a significant impact on both scientific and clinical advancements.

Areas for Improvement:

While Dr. Antohe’s research is highly regarded, there is potential for greater integration of her research with cutting-edge technologies in bioinformatics and computational biology. This could further expand her work on proteomics and molecular mechanisms. Additionally, there is an opportunity for broader outreach to apply her findings in practical therapeutic contexts through collaborations with pharmaceutical companies or clinical trials. Expanding her influence in translational research could have a larger impact on public health, especially in diseases such as diabetes and cardiovascular disorders.

Education:

Dr. Felicia Antohe holds a Master’s degree in Biophysics from the University of Bucharest (1977). She completed her PhD in Cellular Biology at the Romanian Academy’s Institute of Cellular Biology and Pathology (1994). In addition to her formal education, she has been a PhD coordinator since 2000 and has contributed significantly to research training at national and international levels. Her work blends theoretical knowledge with cutting-edge lab techniques in molecular biology, proteomics, and immunology.

Experience:

Dr. Antohe’s research experience spans numerous roles. She is currently the Principal Investigator and Member of the Scientific Council at the Romanian Academy’s Institute of Cellular Biology and Pathology. She has also worked as a visiting scientist at prestigious institutions like McGill University, University of Alberta, and Max Planck Institute. She has coordinated over 44 research projects, including national and international grants, and is actively involved in multiple collaborative research efforts across Europe and beyond. Her leadership in cell biology and proteomics is widely recognized.

Awards and Honors:

Dr. Antohe has received numerous awards, including the EURESCO Prize (2001), the BIO-RAD Laboratories Prize for valuable research (2002), and the Romanian Academy Emil Racovita Prize (1991). She has also won multiple international recognitions for her scientific contributions, such as the Best Poster award at the “8th International Conference on Vascular Endothelium” (2005), and various fellowships and grants from organizations like COST and the European Science Foundation.

Research Focus:

Dr. Antohe’s research focuses on endothelial cell biology, particularly transcytosis, endocytosis, and cell receptor mechanisms in both health and disease. She investigates the bio-pathology of atherosclerosis, diabetes, and immune disorders, with particular attention to the transport of macromolecules across vascular cells. Her work also explores the role of monoclonal antibodies as diagnostic and therapeutic tools. She applies proteomic techniques to study endothelial cell function, aiming to understand vascular biology at molecular and cellular levels.

Publications Top Notes:

  • The MHC class I-related receptor, FcRn, plays an essential role in the maternofetal transfer of γ-globulin in humans 📄
  • Functional expression of the MHC class I-related receptor, FcRn, in endothelial cells of mice 📄
  • Transcytosis of plasma macromolecules in endothelial cells: a cell biological survey 📄
  • Expression of functionally active FcRn and the differentiated bidirectional transport of IgG in human placental endothelial cells 📄
  • Analytical techniques for multiplex analysis of protein biomarkers 📄
  • Functional ultrastructure of the vascular endothelium: changes in various pathologies 📄
  • Effect of enoxaparin on high glucose-induced activation of endothelial cells 📄
  • Albumin-binding proteins function in the receptor-mediated binding and transcytosis of albumin across cultured endothelial cells 📄
  • Carbapenemase-Producing Klebsiella pneumoniae in Romania: A Six-Month Survey 📄
  • Establishment of a pure vascular endothelial cell line from human placenta 📄

Conclusion:

Dr. Felicia Antohe is an outstanding researcher whose work has greatly advanced our understanding of endothelial cell biology, molecular transport, and disease mechanisms. Her combination of technical expertise, leadership in multiple high-impact research projects, and numerous prestigious awards positions her as an ideal candidate for the Research for Molecular Cell Biology Award. While there is always room to expand her research applications, her contributions to science are already substantial and impactful.

 

 

 

Gonca Çelik | Developmental Cell Biology | Best Researcher Award

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Assoc. Prof. Dr. Gonca Çelik | Developmental Cell Biology | Best Researcher Award

Assoc. Prof. Dr. Gonca Çelik , Karadeniz Technical University , Turkey

Assoc. Prof. Dr. Gonca Çelik, born on April 18, 1984, is a distinguished academic with an extensive background in chemistry, particularly in organic chemistry. She earned her bachelor’s degree in Chemistry Teaching from Karadeniz Technical University (KTU) in 2008. Later, she pursued a doctorate in Chemistry, specializing in Organic Chemistry, from KTU, completing her Ph.D. in 2017. With an h-index of 12, she has made significant contributions to scientific research, including 38 publications in SCI-Expanded indexed journals. Dr. Çelik is also recognized for her involvement in various research projects, particularly in enzyme inhibition, molecular docking studies, and the synthesis of bioactive compounds. Fluent in both Turkish and English, she actively collaborates internationally and has authored several impactful publications related to drug development and the synthesis of biologically active compounds, contributing to fields such as medicinal chemistry and biochemistry.

Publication Profile:

Scopus

Strengths for the Award:

Assoc. Prof. Dr. Gonca Çelik is a highly accomplished researcher with a strong background in organic chemistry, particularly in drug development and biological evaluations. Her significant contributions to the field are reflected in her 38 publications in SCI-Expanded indexed journals. She has demonstrated expertise in synthesizing bioactive compounds, investigating their biological activities, and applying molecular modeling techniques, including molecular docking and ADMET studies. Her work on the synthesis of flavonol derivatives, which are potential inhibitors of SARS-CoV-2, underscores her impact on global health research. Dr. Çelik has also been an active participant in multiple national and international research projects, including Tubitak-funded projects, focusing on enzyme inhibition and molecular modeling for disease treatment. Her leadership in scientific research, combined with a solid academic background, positions her as a valuable contributor to scientific advancements.

Areas for Improvement:

While Dr. Çelik’s research is impressive, there is room for greater visibility and dissemination of her findings to broader interdisciplinary audiences. Increased collaboration with researchers from other scientific fields, such as pharmacology and clinical medicine, could enhance the real-world application of her work, particularly in the development of drug therapies. Expanding her research focus to include more clinical trials or translational research could help bridge the gap between laboratory findings and practical medical applications. Additionally, increasing her involvement in scientific outreach or mentorship programs could further contribute to the development of the next generation of researchers in chemistry and pharmacology.

Education:

Dr. Gonca Çelik’s educational journey began with a Bachelor’s degree in Chemistry Teaching from Karadeniz Technical University (KTU) in 2008. She then pursued postgraduate studies, enrolling directly in the doctoral program in Chemistry at KTU, where she specialized in Organic Chemistry, completing her Ph.D. in 2017. Her doctoral research focused on developing bioactive organic compounds with potential therapeutic applications. Dr. Çelik has also gained international exposure during her Master’s studies, spending time at Clausthal University of Technology in Germany in 2014, which broadened her academic perspective and research experience. Over the years, her educational background and research expertise have provided a solid foundation for her ongoing contributions to the field of organic chemistry, particularly in medicinal chemistry, enzyme inhibition, and molecular docking studies. This strong academic base supports her continued success as an academic and researcher in the field of chemistry.

Experience:

Dr. Gonca Çelik’s academic and professional journey spans over a decade. She began her career as a Research Assistant at Karadeniz Technical University (KTU) in 2010, where she worked until 2017. During her time at KTU, she contributed to several research projects in the field of chemistry, including organic synthesis and biological evaluation of compounds. Her academic work has led her to publish multiple papers in international and national journals. In 2014, she expanded her research horizons by spending time as a Master Student at Clausthal University of Technology in Germany, further strengthening her academic profile. Dr. Çelik has also been involved in various Tubitak and KTU-supported research projects, particularly focusing on enzyme inhibition, molecular docking, and bioactive compound synthesis. She has held roles in multiple projects, such as the synthesis of flavonol derivatives for drug development and the study of antimicrobial and anticancer properties of organic compounds.

Research Focus:

Dr. Gonca Çelik’s primary research interests lie in the field of organic chemistry, with a particular focus on bioactive compound synthesis, enzyme inhibition, and molecular docking studies. Her research aims to discover and develop novel organic molecules with potential therapeutic applications, especially in drug development for diseases such as COVID-19. She has worked extensively on synthesizing flavonol derivatives and other bioactive compounds, investigating their enzyme inhibition efficiencies and biological activities. Dr. Çelik’s work in molecular modeling and computational studies (e.g., ADMET and molecular docking) complements her experimental research, helping to predict the behavior of synthesized compounds at the molecular level. Her research has contributed to the development of potential inhibitors for viruses and other diseases, highlighting her interdisciplinary approach that bridges chemistry and pharmacology. She has been involved in several national and international projects, contributing to the scientific community through her publications and innovative research efforts.

Publications Top Notes:

  1. Synthesis, Biological Evaluation and Molecular Docking Studies of Flavonol-3-O-β-D-glycoside as a Potential Inhibitor of SARS-CoV-2 Main Protease (3CLpro) in Drug Development for COVID-19 🧬💊
  2. Synthesis, structural, spectroscopic (NMR, FT-IR and UV–Vis), NLO, in silico (ADMET and molecular docking) and DFT investigations of a flavonol derivative 2-(4-chlorophenyl)-7-fluoro-3-hydroxy-4H-chromen-4-one 🧪🔬
  3. Antimicrobial, cytotoxic, antiviral effects, and spectroscopic characterization of metabolites produced by fusarium oxysporum yp9b 🦠💉
  4. Biological activity, and volatile and phenolic compounds from five Lamiaceae species 🌱🧴
  5. Synthesis, spectroscopic, and photophysicochemical behavior of Zn(II) and Mg(II) phthalocyanine–chalcone conjugates ⚙️🧑‍🔬
  6. New chalcone-3-O-glycoside derivatives: Synthesis and characterization 🧪🔬
  7. Synthesis and characterization of some new pyrazolines and their inhibitory potencies against carbonic anhydrases 🧫💥

Conclusion:

Dr. Gonca Çelik’s academic achievements, extensive publication record, and leadership in research make her a strong contender for the Best Researcher Award. Her work has made substantial contributions to drug development, specifically in the context of COVID-19 treatment, enzyme inhibition, and molecular modeling. With a solid foundation in chemistry and a forward-looking approach to interdisciplinary research, she continues to push the boundaries of scientific knowledge. Enhancing her outreach efforts and fostering collaborations with clinical researchers will further amplify the impact of her work on global health. Therefore, Dr. Çelik’s research excellence, combined with her potential for future advancements, makes her a deserving candidate for the Best Researcher Award.