Shuxin Han | Molecular Mechanisms Signaling | Best Researcher Award

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Dr. Shuxin Han | Molecular Mechanisms Signaling | Best Researcher Award

Dr. Shuxin Han | Xinjiang University | China

Dr. Shuxin Han is a distinguished molecular biologist and professor at Xinjiang University, widely recognized for his pioneering work in hepatobiliary and metabolic biology. With a research career spanning over two decades, Dr. Han has made major contributions to understanding how Kruppel-like factors, especially KLF15, regulate endobiotic and xenobiotic metabolism, impacting drug detoxification and metabolic disease mechanisms. He earned his Ph.D. from Kent State University and has held prestigious positions at Harvard Medical School and Case Western Reserve University. His groundbreaking studies have been published in high-impact journals like Nature Metabolism and Nature Communications, with several articles naming him as first or corresponding author. In addition to research, Dr. Han serves as a reviewer for top-tier journals in pharmacology, hepatology, and clinical science. He is also an academic leader, currently shaping the next generation of scientific talent and metabolic disease research in China.

Publication Profile: 

Scopus

Education:

Dr. Shuxin Han began his academic journey in Animal Sciences, earning a bachelor’s degree from Anhui Agricultural University (1994–1998). He advanced to a research assistant role at Peking University (1999–2000), where he deepened his scientific foundation. He then moved to the U.S. to pursue a Master’s in Biology at Temple University (2000–2003), followed by a Ph.D. in Molecular Biology from Kent State University (2004–2009), focusing on metabolic biology and gene regulation. This progression from general animal sciences to highly specialized molecular biology reflects a systematic and deep commitment to biomedical research. His strong academic preparation laid the foundation for a research career investigating how transcriptional regulators impact health and disease. Dr. Han’s training spans world-class institutions across both China and the United States, equipping him with diverse scientific perspectives and techniques.

Experience:

Dr. Shuxin Han has accumulated rich research and academic experience over nearly 30 years. His early career included a pivotal research assistant role at Peking University, followed by advanced training in biology and molecular biology at Temple and Kent State Universities. He completed prestigious postdoctoral training at Harvard Medical School (2009–2012) and Case Western Reserve University (2012–2015), where he later became a Senior Research Associate (2015–2019). He returned to China in 2019 as a Researcher at the University of Science and Technology of China First Affiliated Hospital, simultaneously engaging in academic duties at the university until 2023. Currently, he serves as a Professor and Academic Leader at Xinjiang University. Throughout his career, Dr. Han has built strong international collaborations, led research groups, and guided innovative projects in metabolic biology, demonstrating his leadership, research excellence, and academic mentorship capabilities.

Research Focus:

Dr. Shuxin Han’s research centers on the molecular regulation of metabolism, particularly focusing on the hepatobiliary and gastrointestinal systems. His work has elucidated the critical role of the Kruppel-like factor (KLF) family, especially KLF15, in controlling endobiotic and xenobiotic metabolism (EXM). These pathways govern how the body metabolizes both internal compounds and external substances like drugs. Dr. Han’s studies have shown that KLF15 acts as a master regulator, influencing drug resistance, liver injury, and metabolic homeostasis. His discoveries offer new insight into personalized medicine and treatment for metabolic disorders and drug-related toxicities. With numerous first-author and corresponding-author publications in journals such as Nature Metabolism, Nature Communications, and Drug Metabolism and Disposition, his work has significantly impacted both fundamental science and clinical applications. He is also active in peer-reviewing for top-tier journals and is recognized for his leadership in translational research.

Publications Top Notes:

  1. Unveiling KLF15 as the Key Regulator of Cyclosporine A Metabolism and Adverse Effects – Drug Metabolism and Disposition, 2025

  2. Distribution and Functional Significance of KLF15 in Mouse Cerebellum – Molecular Brain, 2025

  3. Personalized Statin Therapy: Targeting Metabolic Processes – Heliyon, 2025

  4. Current Status and New Directions for Hepatocellular Carcinoma Diagnosis – Liver Research, 2024

  5. KLF15-Cyp3a11 Axis Regulates Rifampicin-Induced Liver Injury – Drug Metabolism and Disposition, 2024

  6. Advancing Drug Delivery and Bioengineering in Liver Research – Bioengineering and Translational Medicine, 2024

  7. Advances in IL-7 Research on Tumor Therapy – Pharmaceuticals, 2024 (Co-author)

  8. Pathogenic Mechanisms in Alcoholic Liver Disease – Journal of Translational Medicine, 2023

  9. Beta-Hydroxybutyrate Effects on iPSC-Derived Cardiac Myocytes – Biomolecules, 2022

  10. Interactions Between Intestinal Flora and Bile Acids – International Journal of Molecular Sciences, 2022 (Corresponding author)

Conclusion:

In conclusion, Dr. Shuxin Han is a highly deserving candidate for the Best Researcher Award. His pioneering work on KLF15 and metabolic regulation has reshaped fundamental understanding in the field of hepatobiliary biology and pharmacology. His academic background, research productivity, international experience, and editorial service all reflect a well-rounded and impactful scientist. While there is room to increase clinical translation and international engagement, the depth, originality, and consistency of his research make him a strong contender for this recognition. Honoring Dr. Han with this award would acknowledge a career dedicated to scientific advancement with substantial implications for human health and drug therapy.

Huicong Wang | Developmental Cell Biology | Outstanding Scientist Award

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Prof. Huicong Wang | Developmental Cell Biology | Outstanding Scientist Award

Prof. Huicong Wang , South China Agricultural University , China

Huicong Wang is a Professor of Pomology and the Director of the Guangdong Litchi Engineering Research Center at South China Agricultural University. With expertise in fruit physiology, Wang has significantly contributed to the research and development of litchi fruit cultivation, focusing on the quality formation and maturation processes. Wang is internationally recognized for advancing the understanding of fruit growth, pigmentation, and metabolic regulation, with particular attention to litchi, a key agricultural product of China. Through a combination of teaching, research, and field-oriented approaches, Wang has improved fruit quality and plant productivity, offering valuable insights into orchard management practices. His works have influenced both academic circles and agricultural practices globally.

Publication Profile:

Scopus

Strengths for the Award:

Professor Huicong Wang is a highly accomplished scientist in the field of pomology, with a specific focus on fruit crop physiology, particularly litchi. His extensive body of research covers key areas such as fruit maturation, biochemical processes, pericarp pigmentation, and sugar metabolism in litchi. His work has significantly enhanced the understanding of fruit quality formation and the physiological mechanisms governing fruit development. Wang’s contributions extend to the impact of environmental conditions on fruit quality, stress physiology, and the application of field management practices. With over a decade of teaching experience and a substantial publication record, he has demonstrated leadership in both academic and research communities. His ability to translate scientific findings into practical applications for improving fruit yield and quality highlights his potential for making meaningful contributions to the agricultural industry.

Areas for Improvement:

While Professor Wang’s research is comprehensive and influential, further international collaboration with researchers in other horticultural fields could enhance the global applicability of his findings. Additionally, expanding his focus on the climate change impacts on fruit crops could be beneficial, as this remains a critical area of concern for global agriculture.

Education:

Huicong Wang received his Bachelor’s degree in Pomology from South China Agricultural University in 1995, followed by a Master’s degree in Pomology in 1998. He obtained his Ph.D. in Pomology in 2001 from the same institution, where he also completed postdoctoral research. In 2007, Wang was a visiting fellow at Cornell University for one year, expanding his academic and research horizons. His doctoral research focused on litchi fruit maturation, pigmentation, and hormonal regulation under the supervision of Professor Huibai Huang. Wang’s academic foundation has provided him with the knowledge and skills needed to investigate various aspects of fruit physiology, particularly in evergreen fruit trees.

Experience:

Professor Huicong Wang has extensive teaching experience at South China Agricultural University, where he lectures on “Physiology of Fruit Trees” and “Fruit Tree Research Methods” to graduate students. He also teaches undergraduate courses such as “Aromatic Plants” and “Fruit Nutrition and Healthcare.” Wang’s research experience is centered around fruit crop physiology, particularly focusing on evergreen fruit trees like litchi. His expertise lies in studying fruit maturation, pigmentation, and biochemical composition changes during ripening. Additionally, he investigates the impact of environmental stress, orchard management practices, and genetic regulation on fruit quality and yield. Wang’s work has contributed to improvements in fruit production and quality through scientific advancements and practical applications.

Research Focus:

Huicong Wang’s primary research focuses on fruit physiology, particularly in the growth, maturation, and quality formation of fruit crops such as litchi. His work investigates the biochemical and hormonal processes involved in the pigmentation of pericarps, sugar accumulation in arils, and changes in the fruit’s physical and chemical properties during ripening. He explores key factors like source-sink relationships, fruit abscission, and the influence of environmental conditions on fruit quality and productivity. Wang also conducts research on stress physiology, flower induction, and the impacts of field management practices on fruit trees. His work aims to optimize production and enhance the quality of fruit crops, ensuring sustainability and increasing agricultural output.

Publications Top Notes:

  1. Zou SC, Zhou MG, Abbas F, Zeng RF, Hu GB, Wang HC*, Huang XM*. 2024. ROS- and CBF- mediated pathways in ripening litchi fruits. Postharvest Biology and Technology 🥭🍃
  2. Yang MC, Wu ZC, Chen RY, Abbas F, Hu GB, Huang XM, Guang WS, Xu YS, Wang HC*. 2023. Single-nucleus RNA sequencing in litchi floral transition. Journal of Experimental Botany 🌱📚
  3. Zou SC, Zhou MG, Abbas F, Hu GB, Wang HC*, Huang XM*. 2023. LcNAC002 transcription factor in litchi anthocyanin biosynthesis. Plant Physiology 🌸🧬
  4. Yang MC, Wu ZC, Huang LL, Abbas F, Wang HC*. 2022. Isolation of high purity nuclei from plants. Cells 🧫🔬
  5. Yi JW, Ge HT, Abbas F, Zhao JT, Huang XM, Hu GB, Wang HC*. 2022. LcHXK1 in regulating fruit abscission in litchi. Tree Physiology 🍊🌿
  6. Abbas F, O’Neill Rothenberg D, Zhou Y, Ke Y*, Wang HC*. 2022. Volatile organic compounds in plant communication. Physiologia Plantarum 🌸🌿
  7. Yi JW, Wang Y, Ma XS, Zhang JQ, Zhao ML, Huang XM, Li JG, Hu GB, Wang HC*. 2021. LcERF2 in regulating litchi fruit abscission. The Plant Journal 🍇📚
  8. Lai B, Du LN, Wang D, Huang XM, Zhao JT, Wang HC*, Hu GB*. 2019. Litchi MYB transcription factor and anthocyanin biosynthesis. MBC Plant Biology 🌺🎨
  9. Xie DR, Ma XS, Rahman MZ, Yang MC, Huang XM, Li JG, Wang HC*. 2019. Thermo-sensitive sterility in litchi. Scientia Horticulturae 🍃🌞
  10. Zhang JQ, Wu ZC, Hu FC, Liu L, Huang XM, Zhao JT, Wang HC*. 2018. Seed development in Litchi chinensis. Horticulture Research 🌱🍇

Conclusion:

Professor Huicong Wang’s robust research, substantial teaching experience, and contributions to the pomology field make him an excellent candidate for the Outstanding Scientist Award. His work in improving fruit productivity and quality, particularly for litchi, aligns with current agricultural needs, positioning him as a leading scientist in his field. By continuing to broaden the scope of his research and fostering international partnerships, he has the potential to further elevate his impact on both the scientific community and the agricultural sector.