Prof. Majid Sadeghizadeh , tarbiat modares univercity , Iran
Dr. Majid Sadeghizadeh is a distinguished Professor and Head of the Genetics Department at Tarbiat Modares University (TMU), Iran. With a Ph.D. in Molecular Biology from Paris, he specializes in Molecular Genetics, with a particular focus on infectious diseases, cancer therapy, and nanobiotechnology. Dr. Sadeghizadeh has contributed extensively to molecular diagnosis, including human Herpes viruses, HIV, and COVID-19, as well as the design of nanomaterials for drug delivery and cancer treatment. His work in cell imaging using carbon dots is groundbreaking. He has published over 200 papers, earned a citation index of 8337, and holds an H-index of 50. Dr. Sadeghizadeh is also the author of several books and has been involved in patenting innovative nano-based products. As an academic leader, he collaborates with global institutions, and his research influences cancer therapy, bioimaging, and drug delivery technologies.
Publication Profile:
Scopus
Strengths for the Award:
Dr. Majid Sadeghizadeh has made significant contributions to the field of cellular imaging, particularly through his research on the application of carbon dots prepared from biomaterials for cell imaging. His expertise in nanobiotechnology, including the design of advanced nanomaterials such as Nano Curcumin and Nano Milk Thistle for cancer therapy and drug delivery, has led to groundbreaking advancements in imaging techniques and therapeutic monitoring. His multi-disciplinary approach, combining molecular biology with nanotechnology, enhances the capabilities of imaging technologies, offering more precise and effective solutions for disease detection and treatment. Additionally, his extensive publication record and high citation index underscore his impact on the scientific community, particularly in areas related to bioimaging and cancer research.
Areas for Improvement:
While Dr. Sadeghizadeh’s work is notable, expanding his research on the integration of imaging techniques with clinical applications could further enhance the translation of his innovations into therapeutic settings. This could involve collaborations with clinical researchers to validate his imaging methods in real-world medical applications, potentially focusing on early detection and personalized medicine.
Education:
Dr. Majid Sadeghizadeh earned his Ph.D. in Molecular Biology from Paris, where he focused on the transcription and replication of human herpesviruses. His educational journey laid the foundation for his groundbreaking contributions to molecular genetics, particularly in infectious diseases, cancer therapy, and nanobiotechnology. He has furthered his academic expertise through numerous collaborations with international research institutions, strengthening his focus on molecular diagnostics and the application of nanomaterials in medicine. His training in Paris instilled in him a strong commitment to advancing molecular genetics research, which continues to drive his innovative work at Tarbiat Modares University. He has guided numerous graduate students and postdoctoral fellows, and his own research has been pivotal in enhancing the scientific understanding of viral infections and cancer treatment. His academic achievements are complemented by his publications, patents, and ongoing contributions to the scientific community.
Experience:
Dr. Majid Sadeghizadeh brings over two decades of experience as a Professor and Head of the Genetics Department at Tarbiat Modares University (TMU), Iran. Throughout his career, he has focused on molecular genetics, developing diagnostic tools for infectious diseases such as Herpes Simplex Virus (HSV), HIV, and COVID-19. His research also extends into nanobiotechnology, where he has made significant strides in creating nanomaterials for cancer therapy and drug delivery. As a principal investigator in the Genetics and Nanobiotechnology Department at TMU, he has led multiple research projects that bridge the gap between molecular biology and practical medical applications. Dr. Sadeghizadeh has published over 200 papers in SCI and Scopus-indexed journals and has contributed to several books on molecular biology and genetic engineering. He has also been involved in various industry projects, such as the industrial production of Nano Curcumin for use as an antioxidant in pharmaceuticals.
Research Focus:
Dr. Majid Sadeghizadeh’s research is at the intersection of molecular genetics, nanobiotechnology, and medical applications. He focuses on the molecular diagnosis of human infectious viruses, such as HSV, HIV, and COVID-19, with an emphasis on improving diagnostic tools and therapeutic strategies. His research in nanobiotechnology aims to design and construct advanced nanomaterials, including Nano Curcumin, Nano Solanine, and Nano Milk Thistle, for targeted cancer therapy and drug delivery. Additionally, Dr. Sadeghizadeh has pioneered the use of carbon dots prepared from biomaterials for cell imaging, advancing the capabilities of non-invasive diagnostics and therapeutic monitoring. His innovative work in these areas has led to the development of novel approaches for drug delivery, cancer treatment, and disease diagnosis. By combining molecular biology with nanotechnology, Dr. Sadeghizadeh’s research continues to push the boundaries of personalized medicine, offering new possibilities for treatment and early detection of diseases.
Publications Top Notes:
- 3D Printing of Biocompatible and Antibacterial Silica-Silk-Chitosan-Based Hybrid Aerogel Scaffolds Loaded with Propolis (2024) 🧪
- Intelligent guide RNA: dual toehold switches for modulating luciferase in the presence of trigger RNA (2024) 🔬
- Inhibition of HIV-1 infection with curcumin conjugated PEG-citrate dendrimer; a new nano formulation (2024) 💉
- Synergistic effect of curcumin and tamoxifen loaded in pH-responsive gemini surfactant nanoparticles on breast cancer cells (2024) 💊
- Inhibitory effect of dendrosomal-nanocurcumin on Burkitt’s lymphoma cells by reducing EBV lytic gene expression (2024) 💀
- Evaluation of the Expression Level of Some Coding and Non-coding Genes in Breast Cancer Samples Based on Bioinformatics and Laboratory Studies (2024) 🧬
- Encapsulation of propolis extracted with methylal in the chitosan nanoparticles and its antibacterial and cell cytotoxicity studies (2024) 🌿
- MicroRNA-203a inhibits breast cancer progression through the PI3K/Akt and Wnt pathways (2024) 💡
- Development of an ostrich-derived single-chain variable fragment (scFv) against PTPRN extracellular domain (2024) 🦢
- CLEC19A overexpression inhibits tumor cell proliferation/migration and promotes apoptosis concomitant suppression of PI3K/AKT/NF-κB signaling pathway in glioblastoma multiforme (2024) 🧠
Conclusion:
Dr. Majid Sadeghizadeh is highly deserving of the Cellular Imaging Award due to his pioneering work in carbon dot-based imaging and his broader contributions to nanobiotechnology in cancer therapy and drug delivery. His research is advancing the capabilities of cellular imaging and holds great promise for improving disease diagnostics and treatments. By fostering further integration of his innovations into clinical practices, Dr. Sadeghizadeh can continue to shape the future of personalized medicine and medical imaging.