Noureddine Allouche | Molecular Mechanisms Signaling | Best Research Article Award

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Prof. Noureddine Allouche | Molecular Mechanisms Signaling | Best Research Article Award

Prof. Noureddine Allouche , Faculty of Sciences of Sfax, University of Sfax , Tunisia

Professor Noureddine Allouche, born in 1971, is a Full Professor of Chemistry at the Faculty of Sciences of Sfax (FSS), Tunisia. He is the Head of the Natural Substances Team in the Laboratory of Organic Chemistry. With over 150 peer-reviewed publications, an h-index of 35, and more than 4500 citations, he is recognized for his impactful research on natural products and environmental valorization. He has led and contributed to multiple national and European research projects, including FP7, H2020, Erasmus+, and ARIMNET. His work focuses on extraction, isolation, and bioactivity of plant-based compounds and sustainable management of industrial waste. Prof. Allouche has supervised 20 Ph.D. theses and 42 M.Sc. students, contributing significantly to scientific advancement in Tunisia and beyond. He is also involved in applied research in green chemistry and cosmetic sciences. His collaborative work and leadership have earned him recognition in the academic and research communities.

Publication Profile: 

Orcid

âś… Strengths for the Award:

  1. High Research Productivity and Impact

    • Over 150 peer-reviewed scientific articles with a h-index of 35 and 4,500+ citations, which reflect sustained academic influence and quality.

    • Contributor to top-tier journals such as Plants, Biomolecules, and Molecules.

  2. Strong Focus on Societal Relevance

    • Work addresses critical environmental issues such as olive mill waste valorisation, bioconversion, and sustainable resource use.

    • Research applied in green chemistry, natural product-based pharmaceuticals, and eco-cosmetics.

  3. International Collaboration and Leadership

    • Coordinator of six major European and international research projects (FP7, H2020, Erasmus+, ARIMNET).

    • Active partnerships with institutions in France, Germany, and the Mediterranean region, showcasing leadership in multidisciplinary and multinational research.

  4. Methodological Rigor and Innovation

    • Use of advanced analytical techniques (e.g., HPLC-HESI-MS/MS, LC-MS/MS, ESI-MS/MS).

    • Integration of green technologies for natural substance extraction.

  5. Mentorship and Academic Development

    • Supervised 20 Ph.D. theses (plus 4 ongoing), 42 Master’s theses, and numerous diploma projects, especially in applied fields like cosmetic science.

🛠️ Areas for Improvement:

  1. Broader International Recognition

    • While highly active in regional and EU collaborations, increased visibility in global North America/Asia-led consortia or global forums could enhance recognition.

  2. Science Communication and Outreach

    • Publishing in public engagement platforms or delivering talks/webinars to non-specialist audiences could expand the impact of his research beyond academia.

  3. Open Access and Data Sharing

    • Encouraging open data practices and reproducibility of extraction and formulation protocols could enhance scientific transparency and citations.

🎓 Education:

Professor Noureddine Allouche earned his Ph.D. in Chemistry from the University of Sfax between 2000 and 2005, focusing on the treatment and valorisation of olive mill waste, a subject that would lay the foundation for his future research career. Following this, he undertook a prestigious postdoctoral training (2006–2007) at the Institute of Natural Products Chemistry of CNRS in Gif-sur-Yvette, France, enhancing his expertise in natural substances and analytical chemistry. His academic foundation was built on rigorous training in organic chemistry, natural products, and environmental biotechnology. These experiences equipped him with robust research methodologies and an interdisciplinary approach, especially in the extraction and biological evaluation of phytochemicals. His educational path reflects a strong commitment to green and sustainable chemistry, positioning him well for leading high-impact research on natural product development and eco-friendly industrial applications.

đź’Ľ Experience:

Professor Allouche has over 20 years of academic and research experience. He currently leads the Natural Substances Team at the Faculty of Sciences of Sfax and supervises a group of over 20 researchers. He has played a vital role in international research collaborations, serving as the national coordinator of six European-funded projects under FP7, ARIMNET, H2020, Erasmus+, and PHC-Maghreb. His experience also includes participation in the INCO-MED project on detoxification and recovery from olive mill wastewater. Prof. Allouche has an extensive mentoring portfolio, having supervised 20 Ph.D. theses (with 4 ongoing) and 42 M.Sc. students. He has authored 150+ articles, two book chapters, and holds two patents. His career reflects a blend of scientific innovation and applied industrial research, particularly in green technologies, bioactive compounds, and waste valorisation. He is also a regular collaborator with European institutions, reflecting his global outlook and leadership in sustainable science.

🔍 Research Focus:

Prof. Noureddine Allouche’s research centers on natural substances chemistry, green extraction methods, and biotechnological valorisation of industrial wastes, particularly from agro-food sources. He has made significant contributions to the identification and biological evaluation of bioactive compounds such as phenolics, flavonoids, and essential oils. His team is particularly active in analyzing plant extracts for their antioxidant, antimicrobial, cytotoxic, and anti-aging activities, often employing advanced techniques like HPLC, LC-MS/MS, and ESI-MS/MS. Another pillar of his work includes developing biopesticides and bio-cosmetics through green and eco-sustainable approaches. He contributes to nanoformulation research and the design of nature-based products aligned with circular economy principles. His interdisciplinary projects bridge chemistry, pharmacology, environmental science, and cosmetic formulation, making his research highly relevant for addressing current scientific and industrial challenges. His recent involvement in projects like GreenCosmIn and 25MAG23 reflects his leading role in European research on sustainable innovation.

đź“š Publications Top Notes:

  1. 🌿 HPLC-HESI-MS/MS Analysis of Phenolic Compounds from Cynoglossum tubiflorus Leaf Extracts (Plants, 2024)

  2. đź«’ Intensification of Biophenols Extraction Yield from Olive Pomace Using Innovative Green Technologies (Biomolecules, 2022)

  3. 🌸 Antioxidant and Antimicrobial Activities of Erodium arborescens Extracts Characterized by LC-HESI-MS² (Molecules, 2022)

  4. 🌿 ESI-MS/MS Analysis of Aeonium arboreum Leaf Extracts and Evaluation of Antioxidant and Antimicrobial Activities (Molecules, 2021)

  5. 🍇 Novel Natural Products for Healthy Ageing from Mediterranean Diet – The MediHealth Project (Molecules, 2018)

🧾 Conclusion:

Professor Noureddine Allouche stands out as a highly qualified and deserving candidate for the Best Research Article Award. His impressive record in sustainable chemistry, natural products research, international project coordination, and scholarly mentorship underlines his academic excellence and real-world impact. His research directly contributes to health, environmental sustainability, and circular economy principles, aligning well with the goals of high-impact, solution-driven science.

Xueru Li | Molecular Mechanisms Signaling | Cell Microenvironment Award

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Ms. Xueru Li | Molecular Mechanisms Signaling | Cell Microenvironment Award

Ms. Xueru Li , Chongqing Medical University , China

Li Xueru is an accomplished researcher and scientist with expertise in clinical laboratory diagnostics. He obtained his Ph.D. in Clinical Laboratory Diagnostics from Chongqing Medical University. Xueru has contributed extensively to scientific research, particularly in the field of cell microenvironment, fibrosis, and oxidative stress. His research has involved collaborations with prestigious organizations, such as the Chongqing Education Commission and Chongqing Natural Science Foundation. Through his academic journey, he has demonstrated a strong commitment to advancing knowledge in biomedical sciences, particularly in the areas of lung fibrosis and cellular response to environmental stress. Li Xueru is an active participant in research projects and has co-authored several influential publications that have contributed to the advancement of molecular biology and clinical diagnostics.

Publication Profile:

Scopus

Strengths for the Award:

Li Xueru’s expertise in clinical laboratory diagnostics, combined with his research in the field of cell microenvironment and fibrosis, positions him as a strong candidate for the Research for Cell Microenvironment Award. His work, especially the study on “Pharmaceutical targeting of succinate dehydrogenase in fibroblasts to control bleomycin-induced lung fibrosis,” highlights his contributions to understanding cellular mechanisms in fibrosis and oxidative stress. His involvement in high-impact research funded by organizations like the Chongqing Education Commission and the Chongqing Natural Science Foundation shows a commitment to advancing scientific knowledge and contributing to both academic and practical advancements in biomedical sciences. Moreover, his ability to bridge fundamental research with clinical applications demonstrates a strength that aligns with the goals of the Research for Cell Microenvironment Award.

Areas for Improvements:

While Li Xueru’s research focus is promising, there is potential to expand his exploration of cellular microenvironment to include other disease models and extend beyond lung fibrosis. Diversifying his research topics could provide a broader understanding of cellular behavior across different tissues and disease states. Additionally, there could be more emphasis on the development of therapeutic interventions, potentially accelerating the translation of his discoveries into clinical practices. Increasing collaboration with international research teams may also offer new perspectives and further enhance the impact of his work.

Education:

Li Xueru earned his Ph.D. degree in Clinical Laboratory Diagnostics from Chongqing Medical University, one of China’s leading medical institutions. His academic background has provided him with in-depth knowledge of diagnostic technologies, clinical pathology, and molecular biology. During his doctoral studies, he developed expertise in understanding cellular behavior and disease mechanisms at the molecular level, with a particular focus on how environmental stress impacts cellular functions. This education laid the foundation for his career in the biomedical field. He has further strengthened his research skills by participating in various projects funded by the Chongqing Education Commission and the Chongqing Natural Science Foundation. His education has been instrumental in shaping his approach to scientific inquiry, fostering a comprehensive understanding of clinical diagnostics, and equipping him to lead innovative research in the cellular microenvironment and disease mechanisms.

Experience:

Li Xueru’s experience spans a wide range of research activities focused on clinical laboratory diagnostics and cell microenvironment. His involvement in multiple high-impact research projects, supported by institutions like the Chongqing Education Commission and the Chongqing Natural Science Foundation, showcases his leadership in advancing scientific knowledge. Xueru has worked closely with interdisciplinary teams to address complex problems in the biomedical field, particularly lung fibrosis and oxidative stress. His research contributions include identifying novel cellular mechanisms involved in disease pathogenesis, improving diagnostic methodologies, and exploring therapeutic strategies for disease management. He has demonstrated a remarkable ability to apply scientific research in real-world contexts, ensuring that his findings have practical applications in medical diagnostics and treatment. His collaborative approach and innovative thinking have positioned him as a key figure in his field, contributing significantly to both academic literature and clinical advancements.

Research Focus:

Li Xueru’s primary research focus revolves around the molecular mechanisms of diseases, particularly lung fibrosis and cellular responses to environmental stressors. He is dedicated to understanding the impact of oxidative stress on cellular functions and its role in disease progression. His research explores the microenvironment of cells in response to various stimuli, including chemical agents like bleomycin. A significant area of his research is the role of succinate dehydrogenase in fibroblasts and its potential as a pharmaceutical target to control lung fibrosis. Through his work, Xueru has contributed to a better understanding of how cells interact with their microenvironment, which is crucial for developing new diagnostic and therapeutic approaches. His innovative studies on cell signaling pathways, fibrosis, and oxidative stress have the potential to transform treatment strategies for diseases related to chronic inflammation and tissue fibrosis.

Publications Top Notes:

  • Pharmaceutical targeting of succinate dehydrogenase in fibroblasts controls bleomycin-induced lung fibrosis 🧬

  • Corrigendum to “Pharmaceutical targeting of succinate dehydrogenase in fibroblasts controls bleomycin-induced lung fibrosis” 🔬

Conclusion:

Li Xueru is a promising candidate for the Research for Cell Microenvironment Award. His significant contributions to the understanding of cellular mechanisms in fibrosis and oxidative stress have led to valuable insights into the pathophysiology of diseases. By focusing on the cell microenvironment and its role in disease progression, his work is advancing scientific knowledge with important implications for diagnostics and therapy. With further diversification of his research and expanded collaborations, Li Xueru has the potential to make even greater strides in the field, ultimately improving patient outcomes and advancing the application of his findings in clinical settings.