Published on 23/09/202523/09/2025 by Cell Biologist Prof. Dr. Rosa M Giraldez-Perez | Intracellular Transport Systems | Innovative Research Award University or Cordoba | Spain Rosa María Giráldez-Pérez is a researcher in the fields of nanotechnology, nanomedicine, physiology, and neuroscience whose scientific contributions focus on the design and application of nanomaterials for therapeutic purposes. Her work has addressed innovative strategies such as gold nanosystems functionalized with antibiotics or anticancer drugs, the development of nanocarriers for leukemia, prostate, liver, and lung cancer treatments, as well as nanoparticle-based approaches to prevent antibiotic resistance. She has also contributed to research in obesity therapy through nanosystems targeting metabolic regulation and in neuroscience through studies on oxidative stress and fragile X syndrome. Her research output includes 81 scientific documents, which have accumulated 911 citations and reflect an h-index of 13, demonstrating both productivity and impact in her field. A significant portion of her publications are in high-impact journals indexed in the Journal Citation Reports (JCR), and several list her as first or senior author, highlighting her leading role in collaborative projects. By integrating expertise from cellular biology, physiology, and nanoscience, her work advances translational biomedical research and offers potential therapeutic solutions for cancer, infectious diseases, metabolic disorders, and neurological conditions. Profiles: Orcid | Scopus Featured Publications: Giráldez-Pérez, R. M., Grueso, E. M., Montero-Hidalgo, A. J., Muriana-Fernández, C., Kuliszewska, E., Luque, R. M., & Prado-Gotor, R. (2025). Daunomycin nanocarriers with high therapeutic payload for the treatment of childhood leukemia. Pharmaceutics, 17(9), 1236. De Diego-Otero, Y., El Bekay, R., García-Guirado, F., Sánchez-Salido, L., & Giráldez-Pérez, R. M. (2024). Apocynin, a selective NADPH oxidase (Nox2) inhibitor, ameliorates behavioural and learning deficits in the fragile X syndrome mouse model. Biomedicines, 12(2887). Lhamyani, S., Gentile, A. M., Mengual-Mesa, M., Grueso, E., Giráldez-Pérez, R. M., Fernandez-Garcia, J. C., … El Bekay, R. (2024). Au@16-pH-16/miR-21 mimic nanosystem: An efficient treatment for obesity through browning and thermogenesis induction. Biomedicine & Pharmacotherapy, 171, 116104. Giráldez-Pérez, R. M., Grueso-Molina, E. M., Carbonero-Martínez, A., Álvarezmárquez, J., Kuliszewska, E., Gordillo-Macías, M., & Prado-Gotor, R. (2023). Synergistic antibacterial effects of amoxicillin and gold nanoparticles: A therapeutic option to combat antibiotic resistance. Antibiotics, 12(8), 81275. Giráldez-Pérez, R. M., Grueso, E., Montero-Hidalgo, A. J., Luque, R. M., Carnerero, J. M., Kuliszewska, E., & Prado-Gotor, R. (2022). Gold nanosystems covered with doxorubicin/DNA complexes: A therapeutic target for prostate and liver cancer. International Journal of Molecular Sciences, 23(24), 15575. Giráldez-Pérez, R. M., Grueso, E. M., Jiménez-Aguayo, R., Carbonero, A., González-Bravo, M., Kuliszewska, E., & Prado-Gotor, R. (2022). Use of nanoparticles to prevent resistance to antibiotics: Synthesis and characterization of gold nanosystems based on tetracycline. Pharmaceutics, 14(9), 1941. Lhamyani, S., Gentile, A. M., Giráldez-Pérez, R. M., et al. (2021). miR-21 mimic blocks obesity in mice: A novel therapeutic option. Molecular Therapy – Nucleic Acids, 26, 401–416. h Grueso-Molina, E. M., Giráldez-Pérez, R. M., Kuliszewska, E., Guerrero, J. A., & Prado-Gotor, R. (2021). Reversible cationic gemini surfactant-induced aggregation of anionic gold nanoparticles for sensing biomolecules. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 610, 125893. Gomes, A., Carnerero-Panduro, J. M., Jiménez-Ruiz, A., Grueso-Molina, E. M., Giráldez-Pérez, R. M., & Prado-Gotor, R. (2021). Lysozyme-AuNPs interactions: Determination of binding free energy. Nanomaterials, 11(8), 2139. Giráldez-Pérez, R. M., Grueso-Molina, E. M., Domínguez-García, I., Pastor-Carrillo, N. M., Kuliszewska, E., & Prado-Gotor, R. (2021). Biocompatible DNA/5-fluorouracil gemini surfactant-functionalized gold nanoparticles as promising vectors in lung cancer therapy. Pharmaceutics, 13(3), 423. Rosa M Giraldez-Perez | Intracellular Transport Systems | Innovative Research Award
Rosa María Giráldez-Pérez is a researcher in the fields of nanotechnology, nanomedicine, physiology, and neuroscience whose scientific contributions focus on the design and application of nanomaterials for therapeutic purposes. Her work has addressed innovative strategies such as gold nanosystems functionalized with antibiotics or anticancer drugs, the development of nanocarriers for leukemia, prostate, liver, and lung cancer treatments, as well as nanoparticle-based approaches to prevent antibiotic resistance. She has also contributed to research in obesity therapy through nanosystems targeting metabolic regulation and in neuroscience through studies on oxidative stress and fragile X syndrome. Her research output includes 81 scientific documents, which have accumulated 911 citations and reflect an h-index of 13, demonstrating both productivity and impact in her field. A significant portion of her publications are in high-impact journals indexed in the Journal Citation Reports (JCR), and several list her as first or senior author, highlighting her leading role in collaborative projects. By integrating expertise from cellular biology, physiology, and nanoscience, her work advances translational biomedical research and offers potential therapeutic solutions for cancer, infectious diseases, metabolic disorders, and neurological conditions. Profiles: Orcid | Scopus Featured Publications: Giráldez-Pérez, R. M., Grueso, E. M., Montero-Hidalgo, A. J., Muriana-Fernández, C., Kuliszewska, E., Luque, R. M., & Prado-Gotor, R. (2025). Daunomycin nanocarriers with high therapeutic payload for the treatment of childhood leukemia. Pharmaceutics, 17(9), 1236. De Diego-Otero, Y., El Bekay, R., García-Guirado, F., Sánchez-Salido, L., & Giráldez-Pérez, R. M. (2024). Apocynin, a selective NADPH oxidase (Nox2) inhibitor, ameliorates behavioural and learning deficits in the fragile X syndrome mouse model. Biomedicines, 12(2887). Lhamyani, S., Gentile, A. M., Mengual-Mesa, M., Grueso, E., Giráldez-Pérez, R. M., Fernandez-Garcia, J. C., … El Bekay, R. (2024). Au@16-pH-16/miR-21 mimic nanosystem: An efficient treatment for obesity through browning and thermogenesis induction. Biomedicine & Pharmacotherapy, 171, 116104. Giráldez-Pérez, R. M., Grueso-Molina, E. M., Carbonero-Martínez, A., Álvarezmárquez, J., Kuliszewska, E., Gordillo-Macías, M., & Prado-Gotor, R. (2023). Synergistic antibacterial effects of amoxicillin and gold nanoparticles: A therapeutic option to combat antibiotic resistance. Antibiotics, 12(8), 81275. Giráldez-Pérez, R. M., Grueso, E., Montero-Hidalgo, A. J., Luque, R. M., Carnerero, J. M., Kuliszewska, E., & Prado-Gotor, R. (2022). Gold nanosystems covered with doxorubicin/DNA complexes: A therapeutic target for prostate and liver cancer. International Journal of Molecular Sciences, 23(24), 15575. Giráldez-Pérez, R. M., Grueso, E. M., Jiménez-Aguayo, R., Carbonero, A., González-Bravo, M., Kuliszewska, E., & Prado-Gotor, R. (2022). Use of nanoparticles to prevent resistance to antibiotics: Synthesis and characterization of gold nanosystems based on tetracycline. Pharmaceutics, 14(9), 1941. Lhamyani, S., Gentile, A. M., Giráldez-Pérez, R. M., et al. (2021). miR-21 mimic blocks obesity in mice: A novel therapeutic option. Molecular Therapy – Nucleic Acids, 26, 401–416. h Grueso-Molina, E. M., Giráldez-Pérez, R. M., Kuliszewska, E., Guerrero, J. A., & Prado-Gotor, R. (2021). Reversible cationic gemini surfactant-induced aggregation of anionic gold nanoparticles for sensing biomolecules. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 610, 125893. Gomes, A., Carnerero-Panduro, J. M., Jiménez-Ruiz, A., Grueso-Molina, E. M., Giráldez-Pérez, R. M., & Prado-Gotor, R. (2021). Lysozyme-AuNPs interactions: Determination of binding free energy. Nanomaterials, 11(8), 2139. Giráldez-Pérez, R. M., Grueso-Molina, E. M., Domínguez-García, I., Pastor-Carrillo, N. M., Kuliszewska, E., & Prado-Gotor, R. (2021). Biocompatible DNA/5-fluorouracil gemini surfactant-functionalized gold nanoparticles as promising vectors in lung cancer therapy. Pharmaceutics, 13(3), 423.