Published on 18/09/202518/09/2025 by Cell Biologist Dr. Maria Antonietta Grignano | Cellular Stress Response | Best Researcher Award Fondazione IRCCS Policlinico San Matteo di Pavia | Italy Dr. Maria Antonietta Grignano is a biologist and specialist in clinical pathology and biochemistry, currently serving as a researcher and head of the Research Laboratory of the Nephrology, Dialysis, and Transplantation Unit at Fondazione IRCCS Policlinico San Matteo. Her research has focused on innovative strategies in kidney transplantation, ischemia-reperfusion injury, and the use of mesenchymal stromal cell-derived extracellular vesicles for organ conditioning. She has contributed to both preclinical and translational studies, with a particular emphasis on engineered vesicles and molecular profiling in transplant immunology. Dr. Grignano has authored over 30 scientific publications indexed in Scopus and Web of Science, contributing to high-impact journals such as the International Journal of Molecular Sciences, Blood Purification, and Transplant International. Her work includes collaborations with national institutions like the University of Pavia and international partners including Columbia University and universities in the Netherlands. As a recognized reviewer for several peer-reviewed journals, she maintains a strong presence in academic publishing. According to Scopus, she has an h-index of 8 with 162 total citations, and 9 citations indexed in Web of Science, reflecting the growing recognition of her work in nephrology and transplant science. Her scientific contributions span experimental design, data analysis, and dissemination of findings. Profiles: Scopus | Orcid Featured Publications: “A Pre-Clinical Study on the Use of the Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitor PEP 2-8 to Mitigate Ischemic Injury in a Rat Marginal Donor Model” “Engineered ATP-Loaded Extracellular Vesicles Derived from Mesenchymal Stromal Cells: A Novel Strategy to Counteract Cell ATP Depletion in an In Vitro Model” “Pre-transplant IE1-specific T-cell response and CD8 + T-cell count as predictive markers of treated HCMV reactivation in kidney transplant recipients” “Atypical Hemolytic Uremic Syndrome Associated with BNT162b2 mRNA COVID-19 Vaccine in a Kidney Transplant Recipient: A Case Report and Literature Review” “The Impact of Serum/Plasma Proteomics on SARS-CoV-2 Diagnosis and Prognosis” “Sputum proteomics in lung disorders” “Induction of Vesicular Trafficking and JNK-Mediated Apoptotic Signaling in Mononuclear Leukocytes Marks the Immuno-Proteostasis Response to Uremic Proteins” “CD73-Adenosinergic Axis Mediates the Protective Effect of Extracellular Vesicles Derived from Mesenchymal Stromal Cells on Ischemic Renal Damage in a Rat Model of Donation after Circulatory Death” “SARS-CoV-2-specific IgG and NCP in vulnerable patients without symptoms” “Liposome Formulation and In Vitro Testing in Non-Physiological Conditions Addressed to Ex Vivo Kidney Perfusion” Maria Antonietta Grignano | Cellular Stress Response | Best Researcher Award
Dr. Maria Antonietta Grignano is a biologist and specialist in clinical pathology and biochemistry, currently serving as a researcher and head of the Research Laboratory of the Nephrology, Dialysis, and Transplantation Unit at Fondazione IRCCS Policlinico San Matteo. Her research has focused on innovative strategies in kidney transplantation, ischemia-reperfusion injury, and the use of mesenchymal stromal cell-derived extracellular vesicles for organ conditioning. She has contributed to both preclinical and translational studies, with a particular emphasis on engineered vesicles and molecular profiling in transplant immunology. Dr. Grignano has authored over 30 scientific publications indexed in Scopus and Web of Science, contributing to high-impact journals such as the International Journal of Molecular Sciences, Blood Purification, and Transplant International. Her work includes collaborations with national institutions like the University of Pavia and international partners including Columbia University and universities in the Netherlands. As a recognized reviewer for several peer-reviewed journals, she maintains a strong presence in academic publishing. According to Scopus, she has an h-index of 8 with 162 total citations, and 9 citations indexed in Web of Science, reflecting the growing recognition of her work in nephrology and transplant science. Her scientific contributions span experimental design, data analysis, and dissemination of findings. Profiles: Scopus | Orcid Featured Publications: “A Pre-Clinical Study on the Use of the Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitor PEP 2-8 to Mitigate Ischemic Injury in a Rat Marginal Donor Model” “Engineered ATP-Loaded Extracellular Vesicles Derived from Mesenchymal Stromal Cells: A Novel Strategy to Counteract Cell ATP Depletion in an In Vitro Model” “Pre-transplant IE1-specific T-cell response and CD8 + T-cell count as predictive markers of treated HCMV reactivation in kidney transplant recipients” “Atypical Hemolytic Uremic Syndrome Associated with BNT162b2 mRNA COVID-19 Vaccine in a Kidney Transplant Recipient: A Case Report and Literature Review” “The Impact of Serum/Plasma Proteomics on SARS-CoV-2 Diagnosis and Prognosis” “Sputum proteomics in lung disorders” “Induction of Vesicular Trafficking and JNK-Mediated Apoptotic Signaling in Mononuclear Leukocytes Marks the Immuno-Proteostasis Response to Uremic Proteins” “CD73-Adenosinergic Axis Mediates the Protective Effect of Extracellular Vesicles Derived from Mesenchymal Stromal Cells on Ischemic Renal Damage in a Rat Model of Donation after Circulatory Death” “SARS-CoV-2-specific IgG and NCP in vulnerable patients without symptoms” “Liposome Formulation and In Vitro Testing in Non-Physiological Conditions Addressed to Ex Vivo Kidney Perfusion”